The Neuroscience of Anger For eons, human beings have recognized the physical sensations, mental, and emotional effects associated with anger. With the advent of fMRI and other brain-imaging technologies, we have been able to identify which parts of the brain “light up” or become activated during an escalation of anger. In this article, we outline the physiological path through the mind-body that anger takes when we first detect a threat of some sort. As we proceed through th